Here is a look at some things to know as you bet the weekend slate of Week 8 college football games.
All lines are courtesy of Westgate Las Vegas SuperBook, and all games are on Saturday unless otherwise specified.
Oklahoma State Cowboys (-7, 64.5) at Texas Longhorns - 12 p.m. ET
Iowa Hawkeyes (-1.5, 47) at Northwestern Wildcats - 12 p.m. ET
Louisville Cardinals at Florida State Seminoles (-6.5, 58.5) - 12 p.m. ET
Tennessee Volunteers at Alabama Crimson Tide (-36, 50.5) - 3:30 p.m. ET
Syracuse Orange at Miami Hurricanes (-17, 59) - 3:30 p.m. ET
Indiana Hoosiers at Michigan State Spartans (-7, 46) - 3:30 p.m. ET
UCF Knights (-7, 64.5) at Navy Midshipmen - 3:30 p.m. ET
Oklahoma Sooners (-14.5, 54) at Kansas State Wildcats - 4 p.m. ET
LSU Tigers (-7, 59.5) at Ole Miss Rebels - 7:15 p.m. ET
Michigan Wolverines at Penn State Nittany Lions (-9.5, 45) - 7:30 p.m. ET
Since losing 49-10 as 17-point underdogs at Michigan last season, Penn State is 13-2-1 ATS in its past 16 games.
This will mark the fourth time Michigan is an underdog under Jim Harbaugh, with this being the biggest spread. The Wolverines are 1-2 ATS with zero outright wins as an underdog under Harbaugh.
USC Trojans at Notre Dame Fighting Irish (-3.5, 65) - 7:30 p.m. ET
Notre Dame is 1-6 ATS with five outright losses in its past six games as a single-digit favorite.
USC is 0-5 ATS in its past five games. The Trojans haven't had six straight ATS losses in a season since 2000, the year before Pete Carroll became their head coach.
Wake Forest Demon Deacons at Georgia Tech Yellow Jackets (-5.5, 47.5) - 7:30 p.m. ET
Kansas Jayhawks at TCU Horned Frogs (-38.5, 58.5) - 8 p.m. ET
Since TCU joined the Big 12 in 2012, it has won all five meetings against Kansas. However, the Jayhawks are 5-0 ATS in those five games, covering each time as an underdog of at least 20 points.
Arizona Wildcats (-3, 61.5) at California Golden Bears - 8 p.m. ET
Wyoming Cowboys at Boise State Broncos (-14, 45) - 10:15 p.m. ET
Colorado Buffaloes at Washington State Cougars (-10, 52.5) - 10:45 p.m. ET