Zambrano was suspended in June after his dugout confrontation with teammate Derrek Lee and manager Lou Piniella during a game against the White Sox at U.S. Cellular Field. He later spent a month on the restricted list and underwent anger management therapy.
He came back strong for the Cubs, going 8-0 in his final 11 starts and showed great command of his changeup, split finger and slider while topping out between 89 and 91 mph with the fastball.
Zambrano said Monday that he would like to start his seventh straight Opening Day for the Cubs.
"Of course I want to be in the Opening Day lineup," Zambrano said. "I want to open the season for the Cubs. The decision is in [manager] Mike [Quade]'s hands. There's nothing I can do about it if he decides on [Ryan] Dempster or [Matt] Garza."
Zambrano has only won one game in his six prior Opening Day assignments. He surrendered two home runs and eight earned runs in 1 1/3 innings in a 16-5 loss to the Atlanta Braves on Opening Day last season.
Bruce Levine covers the Cubs for ESPNChicago.com and ESPN 1000.