Soriano injured himself after trying to beat out an infield grounder. Blake DeWitt took his spot in the lineup, playing left field.
DeWitt went 3-for-4 with a triple and an RBI.
Soriano came into the game hitting .273 with 12 homers and 29 RBIs. Soriano will have an MRI.
The Cubs had already placed utility infielder Jeff Baker on the 15-day disabled list earlier Monday, a day after putting Reed Johnson on the DL with back spasms. Johnson is hitting .367 with two home runs and 18 RBIs in 34 games.
Sahadev Sharma is a regular contributor to ESPNChicago.com. Information from The Associated Press was used in this report.