"It was a collective decision," Bulls coach Tom Thibodeau said before the game. "We gathered the information, looked at where we were in the schedule and we decided it was in the best interest of everyone to have him sit this one out."
Rose, the reigning MVP, also missed Monday's loss against the Memphis Grizzlies as he rested a toe condition on his left foot. Rose said it's turf toe, but Thibodeau said it was a sprain.
"He's usually a pretty quick healer so he'll get his treatment, then we have a couple days off, so we'll see where he is after that," Thibodeau said. "He usually responds well to treatment."
Thibodeau also said he had no regrets about playing Rose in the previous two games.
"You base your decisions on the information you have at that particular time," Thibodeau said. "So he felt that he was feeling better. We've played a number of games in a short amount of time so we just want to be smart. A lot of guys are hurting right now, but we don't want to take any chances."
Rose, who did not participate in the Bulls' late afternoon shootaround at the United Center and was still wearing a walking boot, said Monday the pain was a "six or seven" on a scale of 1-10.
Rose is averaging 20.8 points and 8.7 assists per game, pushing the Bulls to a league-best 12-3 start.
Nick Friedell covers the Bulls for ESPNChicago.com. Information from The Associated Press was used in this report.