Hossa was in the lineup despite missing Friday's practice and Saturday's morning skate.
Hossa was a late scratch from Game 3 against the Boston Bruins on Monday due to an unspecified upper-body injury. He sat out the team's morning skate on Wednesday and played in Game 4 in Boston later that night.
Hossa had one assist and four shots on goal and played 19:07 in the Blackhawks' 6-5 overtime win in Game 4 that tied the series 2-2. Hossa said he felt "so-so" during Game 4, but he was happy he played and helped out in the win.
Coach Joel Quenneville said Saturday he expected Hossa's play to improve in Game 5.
"He's fine; he's going to play," Quenneville said. "It looks like he should be better."
Hossa is tied for second on the Blackhawks with 16 playoff points this season. He has seven goals, nine assists and a plus-8 rating in 20 games.
Quenneville said after Friday's practice he expected Hossa to be able to play in all roles as he has throughout the season. Hossa is utilized on the top two lines and on the power play and penalty kill by Quenneville. Hossa averaged 18:12 of ice time during the regular season and has averaged 20:15 during the playoffs.
"We expect him to be the same," Quenneville said on Friday. "Once thing about [Hossa's] production offensively or responsibility defensively or complementing our team game in all facets of the game is what we look for. Consistency of what he brings day in, day out to our game is what makes him a special player and a valuable addition to our team, and I think all areas we're going to be leaning on him. No matter where we put him you know you're going to get the job done. I think I would expect him to be a lot more comfortable even going into [Saturday's] game."
Hossa was replaced by Jamal Mayers on the Blackhawks' second line during the morning skate on Saturday. Mayers also filled in for Hossa during the team's morning skate prior to Game 4.
Game 6 will be in Boston on Monday. If necessary, Game 7 will be in Chicago on Wednesday.