The senior wide receiver suffered a hamstring injury during practice Monday, the school confirmed, and there is no timetable for his return.
"Shipley has a hamstring pull, don't know the timetable on that," Texas coach Charlie Strong said Wednesday. "I don't think it's very severe. We'll try to get him back as quickly as possible."
Shipley has 159 career receptions for 1,933 receiving yards and 10 touchdowns in 36 games. He played through a groin issue last season after having preseason surgery and finished with 589 yards and one TD on 56 receptions.
The Longhorn offense is already missing four dismissed players and two more who were suspended. Wide receivers Kendall Sanders and Montrel Meander and running backs Joe Bergeron and Jalen Overstreet were kicked off the team last week.
Another Texas wideout, Marcus Johnson, was sidelined while recovering from minor nasal surgery but returned to practice Wednesday.
"Warrick is getting a lot of work and Harris is getting a lot of work," Strong said. "With five freshmen, it gives us a chance to look at them too."