The No. 3 Florida State Seminoles will be lying in wait as the two programs will face off in their season openers on Sept. 2 in Atlanta.
It is the fourth time that Alabama coach Nick Saban will open as the favorite in the coaches' poll. All three previous times, however, the Crimson Tide have failed to win the national title, including last year's loss to Clemson in the CFP National Championship Game.
The last preseason No. 1 in the coaches' poll to win the national title was USC in 2004. The Trojans open this season at No. 4.
Overall, the SEC placed six teams in the top 25, with Alabama joined by LSU (12), Auburn (13), Georgia (15), Florida (16) and Tennessee (24). The Big 12 and ACC placed five teams in the poll.