Marve has been battling right knee soreness since the middle of training camp. He missed the final eight games of last season after tearing the anterior cruciate ligament in his left knee.
Boilermakers coach Danny Hope said Tuesday that Caleb TerBush will start on Saturday and that he'll try to get Marve on the field.
"He can help us win. We want Robert Marve to play, we want him in the games," Hope said.
TerBush has started Purdue's first two games, but Hope has talked extensively about playing two quarterbacks in games, even after projected starter Rob Henry sustained a torn ACL in late August.
Marve completed 67 of 99 passes for 512 yards with three touchdowns and four interceptions in three-plus games in 2010. He passed for 1,293 yards with nine touchdowns and 13 interceptions for Miami as a freshman in 2008.
Adam Rittenberg covers Big Ten football for ESPN.com. He can be reached at email@example.com