Mustafizur Rahman suffered an ankle twist during training on Saturday, ruling him out of the first ODI in Kimberley on Sunday. Bangladesh manager Minhajul Abedin said that Mustafizur could be out for the rest of the tour.
"Mustafizur twisted his ankle during the warm-up before training," Minhajul, Bangladesh's chief selector and team manager for this tour, told the Daily Star. "He won't play tomorrow.
"We can't tell yet if he will be available for the rest of the series. We'll know more after we go to Cape Town [for the second ODI in Paarl], we haven't done a scan yet."
The incident reportedly took place while playing football ahead of a training session in Kimberley.
Bangladesh have suffered a difficult tour so far, after big defeats in the Test series, with Mustafizur one of the bright spots in an otherwise abysmal bowling performance. They do, however, have Mashrafe Mortaza and Shakib Al Hasan back for the ODIs.