If the Cowboys can't defeat San Diego, it would be their third straight loss and put them under .500, all but ending their postseason hopes.
With Ezekiel Elliott out due to a suspension and linebacker Sean Lee likely out because of hamstring injury, the Chargers are favored on the road in their matchup vs. the Cowboys.
Dallas Cowboys All-Pro left tackle will return from a groin injury to play Thursday against the Los Angeles Chargers.
Are you not entertained?
Two Thanksgiving games fall among the top matchups of the week, including the Chargers versus the Cowboys at 4:30 p.m. (ET). Dallas has lost back-to-back games by 20+ points for the first time since 2004. And since starting the season 0-4, the Chargers have won four of their last six games.
NFL Nation reporters predict the outcomes for Week 12's games including Thursday's big NFC North matchup between the Vikings and the Lions.
If Dan Bailey isn't ready to resume all kicking duties on Thursday, the Cowboys could be in a tough spot when choosing the 46-man active roster.
The Horned Frogs need a win over Baylor on Friday to set up their rematch with the Sooners for the Big 12 championship.
Preparing for a Thursday game after a Sunday night matchup is a little like cramming for a test. Here's how the Cowboys pull off the quick turnaround.
Nathan MacKinnon had three assists, including one off a faceoff with a second remaining in the second period, and the Colorado Avalanche beat the Dallas Stars 3-0 on Wednesday night to remain nearly unbeatable at home.
Spencer Haldeman scored 15 points to help Northern Iowa beat SMU 61-58 in Wednesday's final first-round game at the Battle 4 Atlantis.
Harrison Barnes banked in a 30-footer at the buzzer to give the Dallas Mavericks a 95-94 victory over the Memphis Grizzlies on Wednesday night.
Hometown freshman guard Jarrett Culver scored a career-high 21 points as Texas Tech beat Wofford 79-56 on Wednesday night.
Baylor HC Scott Drew chats with Seth Greenberg about the start of the Bears' season, including the importance of upperclassman leadership, the biggest improvements he has seen player-wise in his program, the strength of the Big 12 as a conference and more.
Jeff Goodman ESPN Insider
Mo Bamba -- the face-up 4-man.
Jeff Goodman ESPN Insider
Here in Portland for practices all day. Looking forward to seeing likely lottery pick Mo Bamba this week.
At 5-5 and on a short week, Jason Witten took time to address his teammates on offense before Thursday's game against the Chargers.
The Cowboys feel that regardless of who left Tyron Smith sees opposite him, he will win the matchup.
Dan Bailey could be ready to return on Thursday night after a groin injury kept him sidelined for the past four games.
Todd Archer ESPN Staff Writer
Left tackle Tyron Smith and linebacker Anthony Hitchens are listed as questionable for Thursday's game against the Los Angeles Chargers because of groin injuries but both expect to be available. Dan Bailey (groin), La'el Collins (back) and Maliek Collins (foot) are also questionable. Sean Lee will miss his second straight game with a hamstring strain.
FPI favors Cowboys over Chargers
The Cowboys have a slight advantage vs. the Chargers on Thanksgiving, according to FPI. Dallas won't play a team that currently has a winning record until Week 16 and could use a win over L.A. to stop its skid and improve its playoff chances.