Hamilton is not in Wednesday's lineup against the Kansas City Royals and will rest the knee for two straight days with Thursday's off day.
Hamilton, who leads the league with a .361 average to go along with 31 homers and 97 RBIs, said he plans on playing the outfield Friday in Minnesota if he doesn't have any setbacks with the knee.
"I'm going to try to get through it for a couple of weeks and see what happens," Hamilton said. "I should be good to play the outfield. It's like having a toothache. It just hurts all the time, but it's that time of the year. I'll get through it."
Hamilton said there are still no plans for an MRI on the knee, but there is a possibility he could get a third cortisone injection in the knee at some point.
"We want to wait as long as possible," Hamilton said. "We'll reevaluate it when it gets to that point. I think this is going to hold me over for a while."
Hamilton said he would come in Friday and do his normal preparation for a game and see how it feels. But for the next two days, he's just going to rest it.