Cruz came out in the 11th inning of Game 6 with a strained right groin suffered on his final at-bat of the game. Napoli rolled his left ankle going awkwardly into second base in the fourth inning but stayed in the game.
Both players, though, were in their usual spots in the lineup. Cruz batted sixth and Napoli seventh.
Napoli has had a memorable World Series, becoming just the second player to have four multi-RBI games in the Fall Classic (Mickey Mantle was the other), and his 10 RBIs in six games so far are the third-most in history, two shy of Bobby Richardson's mark in 1960.
Napoli had an RBI in Game 6 and make a nice throw to pick off Matt Holliday with the Cardinals threatening for more in the sixth.
Cruz was the AL Championship Series MVP with six homers and 13 RBIs and has two homers and three RBIs in the World Series with a .238 average. Cruz said after Game 6 that despite groin pain, he would be in the lineup.
Richard Durrett covers the Rangers for ESPNDallas.com.