"It will be all right," Chandler said after the game. "It'll probably take about a week to heal."
If that's the case, it leaves Chandler's status for the season opener in question.
Chandler suffered the injury trying to block a layup by Orlando's Dwight Howard just before halftime of the Magic's 101-76 victory -- their 21st straight in the preseason.
The Mavericks also may be without shooting guard Roddy Beaubois for the opener. The second-year player is still recovering after having surgery for a broken left foot suffered in early August while working out with the French national team in preparation for the FIBA World Championships.
Jeff Caplan of ESPNDallas.com and The Associated Press contributed to this report.