To help you set your lineups and avoid starting a player who won't take the field, we will post fantasy-relevant updates and analysis here as NFL teams release their Sunday inactive lists before kickoff. Any rankings cited in this column come from our ESPN Fantasy staff ranks.
Refresh often for the latest information.
Ruled out before Sunday
LB Deone Bucannon (ankle), RB Brian Hill (ankle), CB Cole Luke (ankle), S Shawn Williams (elbow), TE C.J. Uzomah (ankle), DE Myles Garrett (ankle), DT Montravius Adams (foot), RB Alfred Blue (ankle), CB Vontae Davis (groin), QB Andrew Luck (shoulder), WR Chester Rogers (hamstring), TE Jordan Leggett (knee), K Sebastian Janikowski (back), FB Jamize Olawale (quad), CB Jimmie Ward (hamstring), CB LeShaun Sims (groin)
Sunday night game, 8:30 p.m. ET
Late games, 4:05 and 4:25 p.m. ET (three scheduled)
QB Cam Newton (shoulder, questionable) -- active
TE George Kittle (hamstring, questionable) -- active
DT Kyle Love (ankle, questionable) -- active
CB Richard Sherman (thigh, questionable) -- active
RB Thomas Rawls (ankle, questionable) -- inactive
WR Tyler Lockett (knee, questionable) -- active
OT Bryan Bulaga (ankle, questionable) -- inactive
Early games, 1 p.m. ET (eight scheduled)
QB Tyrod Taylor (concussion, questionable) -- active
WR Jamison Crowder (hip, questionable) -- active
C Spencer Long (knee, questionable) -- active
LB Cory James (knee, questionable) -- active
DE Khalil Mack (knee, questionable) -- active
S Tashaun Gipson (ankle, questionable) -- active
RB T.J. Yeldon (hamstring, questionable) -- inactive
WR Kenny Golladay (ankle, questionable) -- active
DE Ezekiel Ansah (knee, questionable) -- active
LB Bud Dupree (shoulder, questionable) -- inactive
RB Terron Ward (hamstring, questionable) -- active
CB Prince Amukamara (ankle, doubtful) -- inactive
WR Markus Wheaton (finger, questionable) -- inactive
G Kyle Long (ankle, questionable) -- inactive
WR John Ross (knee, questionable) -- inactive
CB Sheldon Price (concussion, doubtful) -- inactive
Updates/analysis (most recent first)
Thomas Rawls (3:05 p.m.): Rawls is indeed out for Week 1. Eddie Lacy should get the start at running back for the Seahawks, but both C.J. Prosise and Chris Carson will get some touches. Carson is probably the back with the most upside -- not just for Week 1, but the season as a whole.
Indianapolis Colts (2:45 p.m.): We often talk early in the NFL season about how we can't really know which defenses will be good or bad based on last year's stats, due primarily to roster turnover. That's particularly true with the Colts, who (as noted by beat writer Zak Keefer) start a completely new 11 today.
Bryan Bulaga (2:40 p.m.): Kyle Murphy is expected to start at RT for the Packers, as Bulaga will not be able to go in Week 1. While it doesn't suddenly make Green Bay's offense something to avoid outright, Bulaga's absence may well put a damper on Aaron Rodgers' numbers.
Zach Zenner (12:10 p.m.): A potential goal-line vulture, Zenner is a healthy scratch today with Dwayne Washington getting the call as the team's lone backup running back. Why? Washington is Detroit's kickoff return specialist, and has deep-league sleeper potential.
John Ross (12:05 p.m.): The rookie wideout hurt his knee in the Bengals' final preseason game and is unable to make his debut today. Brandon LaFell and Tyler Boyd both get a minor fantasy boost as a result.
Jamison Crowder (11:55 a.m.): The Washington wideout is indeed active. Even if there's some lingering impact from the hip injury, Crowder could easily have a big day against a depleted Philadelphia secondary.
Ezekiel Ansah (11:40 a.m.): Ziggy may end up on a snap count, but the good news -- at least long-term for the Lions D/ST -- is that the veteran defensive end is going to be active for Week 1 action. Ansah believes he's ready to play a full 60 minutes, but we'll see about that.
T.J. Yeldon (11:40 a.m.): With Leonard Fournette now in the Jacksonville backfield, Yeldon had already lost a ton of fantasy value, but he may yet still have some flex impact down the road, should he get healthy. Chris Ivory is the other RB option on the Jaguars.
Kyle Long (10:15 a.m.): Still not all the way back from his ankle surgery, Long might not be ready to handle game action today. As such, a realigned offensive line could result in a less-than-stellar day for RB Jordan Howard, and a few extra sacks for Atlanta's D/ST.
Markus Wheaton (9:20 a.m.): After starting the week only being able to catch Nerf footballs because of his broken finger, the Chicago wideout -- though he has since graduated to real footballs -- is not likely to play in Week 1. Kendall Wright and Kevin White are the expected starters.
Odell Beckham Jr. (8:10 a.m.): It's going to be quite the roll of the dice to start OBJ in Week 1 for your fantasy team, given the Sunday night kickoff and his status as a game-time decision in the Giants' opener. Adam Schefter reports that there is "serious doubt" as to whether or not he will play, so unless you have a backup plan ready to go on Monday night, you may want to -- tough as it may be -- sit the wide receiver today.
Sebastian Janikowski (7:35 a.m.): With the big-legged fantasy veteran having been placed on injured reserve, the Raiders have signed Giorgio Tavecchio from their practice squad to handle kicking duties. He is potentially eligible to return to the team after Week 8, but fantasy owners should never wait on a kicker, even one with Janikowski's track record.
Seattle Seahawks (7:30 a.m.): There may be many Seahawks listed on the injury report headed into Sunday, but Thomas Rawls appears to be the only fantasy-relevant player whose participation in Week 1 is still on the iffy side. He's a game-time call. Richard Sherman, Tyler Lockett and Frank Clark are all expected to play.
Official Sunday inactives should begin coming in at approximately 11:30 a.m. ET for the early games, 2:30 p.m. ET for the late games and 7 p.m. ET for the Sunday night game.