Right fielder Collin Cowgill also came forward and slid toward the ball. Kendrick still attempted to make the play and bent his left leg awkwardly while trying to avoid Cowgill, losing the ball from his glove.
Kendrick stayed down for a long moment before the Angels' medical staff eventually helped him off the field, but he appeared to be putting some weight on his leg.
"I was in a lot of pain at the time," Kendrick said. "It's really sore, but I can put a little bit of pressure on it, so that's always a good sign."
One inning later, the Angels announced Kendrick had hyperextended his knee.
"Hopefully it'll only be a couple of days," Kendrick said. "It's the first time I've ever hyperextended my knee, so it's something that I wish wouldn't have happened. But me and Cowgill were both trying to make a play on the ball. I didn't even really see him at all, and the next thing I know, we're running into each other."
Kendrick began the night batting .302 with 11 homers and 47 RBIs. He has been a valuable offensive contributor with the absence of injured first baseman Albert Pujols and the season-long struggles of outfielder Josh Hamilton.