Smith did not travel with the Hoyas to Indianapolis for Saturday's game against Butler.
Smith also missed Georgetown's previous game, a 70-52 loss at Providence on Wednesday.
This is the second straight game Smith has missed for this reason. He didn't go to the Providence game, either.
Smith is averaging 11.5 points in 19.9 minutes per game for the 10-4 Hoyas.
Second semester classes started Wednesday at Georgetown.