Grudzielanek had a previous injury to his left knee that became worse Saturday when he slid safely home on a squeeze play during the Cardinals' 4-2 win over the Giants.
The knee swelled and Grudzielanek spent the night at Barnes-Jewish Hospital West in St. Louis County. He was discharged Sunday but was not at the game.
Manager Tony La Russa was not available before Sunday's game but said on his radio program on KMOX that Grudzielanek was expected to be sidelined for at least two to three games.
Perez (strained right oblique) returned to Los Angeles and is scheduled to be examined Monday by Dr. Frank Jobe.
Jackson was 3-7 with an 8.62 ERA in Triple-A Las Vegas and 6-4 with a 3.48 ERA for Jacksonville.
The right-hander has inflammation in his throwing shoulder, the team said. The Giants called up right-hander Brian Cooper from Triple-A Fresno.
Walker's lack of velocity concerned ,anager Felipe Alou.
"We gave him two days and we got 88, 89 mph," Alou told the San Jose Mercury News. "He's a guy who throws 95, 96. He's a big guy with a lot of courage, but he's never done what he's doing now, closing games."
Walker is 3-4 with 4.86 earned run average and 22 saves. He became the Giants' closer May 12.
Seattle Mariners: Clint Nageotte walked off the mound, his eyes wide with disbelief. The Mariners' young right-hander, recalled from the minors just hours earlier, entered the game in relief to start the seventh inning Sunday against Minnesota. Nageotte's first pitch sailed well over the head of Lew Ford.
Ford hit a three-run homer in his previous at-bat, so umpire Larry Poncino was suspicious. He ran out from behind the plate and ejected the stunned Nageotte -- prompting a futile argument from Mariners manager Mike Hargrove.
"The umpire absolutely, totally overreacted," Hargrove said. "He's not throwing at anybody, least of all Lew Ford. If we throw at somebody, we'd throw at Joe Mauer."
Nageotte claimed that he slipped on the rubber, causing him to lose control of the ball.
"I was not trying to hit him," he said. "That was the last thing going through my head."
Poncino, however, didn't see it that way.
"The kid can say what he wants," he said. "There's no doubt in my mind he was throwing at him."
The Twins weren't offended.
"I'm sure he's just trying to throw a strike in that situation," Ford said.
"I really feel bad for the kid," Gardenhire said.
Information from The Associated Press was used in this report.