The Brewers activated baseball's all-time saves leader from the disabled list prior to Sunday's game against the Houston Astros.
Hoffman had been on the DL since March 30 with a strain on his right side. Milwaukee signed him in the offseason.
The Brewers entered Sunday's game leading the major leagues with six blown saves. Milwaukee used six pitchers Saturday night in a 9-8 win in 11 innings.
"I asked Trevor if he's got three or four innings in him," manager Ken Macha joked.
Hoffman has 554 career saves. To make room for him, the Brewers optioned lefty R.J. Swindle to Triple-A Nashville.