Indians manager Manny Acta said after a 4-3 loss in 11 innings that Cleveland will add a player to take Cabrera's spot on the roster Tuesday.
Cabrera will be re-examined Wednesday and the possibility of surgery will be discussed.
Trainers placed a protective wrap on Cabrera's forearm.
Cabrera was positioned on the first base side of second and Peralta was playing near the normal shortstop spot as part of a defensive shift.
After being examined behind second base, Cabrera was driven toward the dugout in a cart and taken off the field.
Cabrera was hitting .284 with a home run and seven RBIs.