The two apparently were protesting Arizona's immigration law. Both were quickly apprehended by security and led off the field. The man ran onto the field from the stands along the first base line and was tackled in foul territory. The woman ran into shallow left field.
They ran onto the field just after Joe Saunders grounded out to open the inning.
There were dueling protests outside the downtown ballpark before the game, with one group favoring the law and the other opposing it. Several police officers kept an eye on the protesters.