Jimenez, who's on the 15-day disabled list with a cracked cuticle on his right thumb, was scheduled to throw Monday to open a three-game series with San Francisco. Instead, Esmil Rogers will face Tim Lincecum and the Giants, while Jimenez starts Tuesday.
Rockies manager Jim Tracy said Friday the decision was made not so much because of the condition of Jimenez's cut but to keep Rogers on his regular pitching schedule.
Lefty Jorge De La Rosa will start Wednesday.
Jimenez allowed six runs, five earned, in his opening day start April 1 against the Arizona Diamondbacks. He's eligible to come off the disabled list Sunday.