Vogelsong, 40, will be honored before the team's game Sunday against the Arizona Diamondbacks.
The Giants drafted Vogelsong in 1998, traded him in 2001 and re-signed him to a minor league deal in 2011. Vogelsong's best years came in his second go-around in San Francisco.
Vogelsong went 13-7 with a 2.71 ERA in 2011 en route to an All-Star selection and won two World Series in San Francisco. He was a key contributor on the 2012 World Series team, pitching to a 1.04 ERA in four starts that postseason.
The righty was also twice seriously injured while batting. Vogelsong had pins inserted into his pitching hand in 2013 after it was broken by a Craig Stammen fastball. He was hit in the face by a pitch in 2016 and needed surgery to repair multiple facial fractures.
On the mound, Vogelsong went 61-75 (4.48 ERA) over his 12-year MLB career that featured a four-season interlude (2007-2010) in Japan.
He spent the entirety of his major league career with the Giants and the Pittsburgh Pirates, playing for each team twice.