The reigning AL MVP and 2012 Triple Crown winner complained to home plate umpire Brian Gorman that he felt he was struck in the right leg by a pitch from White Sox starter Chris Sale.
After fouling off the next pitch, Cabrera continued complaining and was ejected by Gorman.
"I tried to get out of the way and (Gorman) said I swung, I was too far out," Cabrera said. "I asked him how could he explain that. I don't know, I just tried to get out of the way. I told him that a couple of times."
Gorman countered, "(Cabrera) was told to stop arguing and continued to argue and he was ejected for continuing the argument."
Leyland came to his player's aid and was also ejected after less than a minute of arguing with Gorman.
"I guess I made my point a little too long and (Gorman) decided to run me and that's fine," Leyland said. "I wasn't questioning the calls at all. I just thought (Cabrera) was an unnecessary ejection."
The ejection was Cabrera's second this season and the fifth of his career. Leyland was tossed for the fourth time this season and for the 72nd time of his career.
Information from The Associated Press was used in this report.