The televised event takes place at the SAP Center. UFC officials confirmed the bout following an initial report by Fox Sports.
Johnson (17-4) is less than two weeks removed from a sterling performance against Phil Davis at UFC 172 in Baltimore. Appearing in the UFC for the first time since 2012, Johnson dominated Davis in a three-round decision for his seventh consecutive win.
Fighting out of Boca Raton, Florida, Johnson is 8-4 in the UFC overall, mostly competing as a welterweight. He made a permanent move to the 205-pound division in 2012.
Nogueira (21-5) hasn't fought since a decision win over Rashad Evans at UFC 156 in February 2013. The 37-year-old was forced to withdraw from multiple fights during that time due to injury.
The Brazilian will finally look to add to a current two-fight win streak that includes wins over back-to-back former champions. Prior to the Evans win, Nogueira finished Tito Ortiz via TKO in the first round of a bout at UFC 140 in December 2011.