In his most recent fight, Mousasi (32-3-2) defeated Ovince St. Preux by unanimous decision on Dec. 17, 2011. That victory was Mousasi's first in Strikeforce since losing his title to Muhammed Lawal in April 2010.
Kyle, who has fluctuated between heavyweight and light heavyweight competition since June 2009, has a professional record of 19-8-1 with one no-contest.
Kyle will enter his fight with Mousasi following a win in his most recent fight. He defeated Marcos Rogerio de Lima by unanimous decision on Sept. 10 in Cincinnati.
Franklin McNeil covers mixed martial arts and boxing for ESPN.com. Follow him on Twitter at www.twitter.com/Franklin_McNeil.