Struve, who stands 6-foot-11, will enter the bout on a two-fight win streak. The 24-year-old has a professional mixed martial arts record of 23-5.
In his most recent fight, Struve defeated Dave Herman by second-round TKO on Feb. 15.
Since being submitted in the first round by Sean McCorkle during his UFC debut on Sept. 25, 2010, Hunt has reeled off three wins in a row.
He cemented his place on the promotion's roster with a first-round TKO of Cheick Kongo on Feb. 26 at UFC 144. Hunt is 8-7 as a mixed martial artist.
The Struve-Hunt bout completes an all-heavyweight main card at UFC 146.
UFC 146 will take place at MGM Grand Garden Arena.