The Strikeforce card scheduled for Nov. 3 in Oklahoma City took another big hit when an injury forced middleweight champion Luke Rockhold to pull out of the event, a source confirmed to ESPN.com Monday.
"Luke is definitely, 100 percent, off the Strikeforce card," the source told ESPN.com. "He injured his left wrist."
TheMMACorner.com, which first reported the news Sunday night, also cited sources close to the situation that Rockhold suffered a wrist injury.
Rockhold, who was slated to defend his title against hard-hitting Lorenz Larkin, becomes the second high-profile fighter to withdraw from the event due to injury.
Mir and Cormier were set to meet in the Nov. 3 main event. Strikeforce has yet to name a replacement for Mir.
Rockhold has a professional record of 10-1. He claimed the Strikeforce 185-pound title in September 2011 with a unanimous decision over then-champion Ronaldo "Jacare" Souza.
Rockhold has successfully defended the title twice. In his more recent outing on July 14, Rockhold defeated Tim Kennedy by unanimous decision.
Strikeforce has not yet revealed if Larkin will remain on the Nov. 3 card.