The promotion has not yet named a city or venue for the event. An official title for the event also has not yet been named.
"As we had anticipated, 2013 will be a very busy year for the Brazilian fans," UFC managing director of international development Marshall Zelaznik said. "We are very happy about this Jan. 19 event, which will kick off our calendar for this year like UFC Rio 2 did in 2012.
"There are still a few details to be settled before we decide the host city. We expect to announce the venue over the next weeks."
Belfort, a former UFC light heavyweight, returns to middleweight after a brief appearance at 205 pounds on Sept. 22 at UFC 152 in Toronto.
He was submitted by current light heavyweight titleholder Jon Jones in the fourth round of that fight. Belfort (21-10) is ranked fifth among 185-pound fighters by ESPN.com.
Bisping (23-4) also competed at UFC 152, defeating Brian Stann by unanimous decision to improve his chances of landing a title shot.
"'The Ultimate Fighter" Season 3 light heavyweight winner, Bisping came up short in a middleweight title eliminator on Jan. 28, losing by unanimous decision to Chael Sonnen.