"It was sore yesterday and he just couldn't go on," said Indiana coach Jim O'Brien, who added that Dunleavy's knee would be reevaluated Monday.
Dunleavy, who missed the first 34 games of the season with an injury to the right knee, left after playing three minutes.
Dunleavy entered the game averaging 15.9 points in 17 games. Indiana is 8-9 since Dunleavy returned on Jan. 7.
Information from The Associated Press was used in this report.