This story has been corrected. Read below.
The procedure will involve the use of a cadaver donor, league sources said. Ezeli has sought a donor for months, sources said, but because of his 6-foot-11 stature, finding a matching donor was problematic. The surgery was scheduled when a donor was recently submitted, sources said.
Ezeli, who has yet to play a game for the Trail Blazers, will officially miss the entire 2016-17 season after signing a two-year, $15.2 million contract with the organization last offseason.
It is unknown exactly how long the recovery process will be, but one source said it could take up to a year.
Other professional athletes have used donated tissue.
Arizona Cardinals quarterback Carson Palmer is the most notable athlete to have had such a procedure. While with the Cincinnati Bengals, Palmer tore the ACL and MCL in his left knee during a 2006 playoff game. It was considered a career-threatening injury.
Palmer received a ligament from Julie De Rossi, who was killed by a drunken driver just 22 months earlier. She was 44. Following surgery and five months of rehabilitation, Palmer was able to run and took the Week 1 snap under center in 2007.
In 2006, the quarterback said of the donor: "Unfortunately, someone had to pass for my recovery to happen. If people didn't donate, my surgery, my recovery and everything else after isn't successful or even possible. It's a lot to think about, just how lucky I am."
Ezeli missed all of his first training camp with the Trail Blazers, as well as exhibition play, after recovering from offseason knee injections that included a bone marrow aspirate. He previously had surgery on his left knee and right knee at different stages during his four-year stint with the Golden State Warriors.
The Blazers announced that Ezeli's surgery will be performed by Dr. Robert LaPrade at the Steadman Clinic in Vail, Colorado.