Porzingis didn't travel with the team to Indiana after missing Sunday's loss to the Orlando Magic due to a right ankle sprain and an illness. He tested the ankle injury before the game, and the Knicks determined that he wasn't healthy enough to play.
Hardaway also didn't travel with the Knicks to Indianapolis due to a stress injury in his left shin. He was an unexpected scratch before tipoff due to the injury.
Knicks coach Jeff Hornacek said the team's medical staff tested Hardaway's injury due to lingering soreness and added that the staff will continue to monitor it.
Hornacek said Hardaway's ailment is unrelated to the left foot plantar fasciitis he played with earlier this month.
The club is hopeful that the shin injury will not sideline Hardaway for an extended stretch of games.
"We'll continue to evaluate him, and we'll find out," Hornacek said.
With Porzingis and Hardaway sidelined, the Knicks will be missing starters who average a combined 43 points against the Pacers. New York (11-11) struggled to generate offense during stretches without Porzingis and Hardaway on Sunday. The club attempted just 10 free throws against Orlando.
It is unclear if Hardaway or Porzingis will return for the Knicks' home game Wednesday against the Memphis Grizzlies.
Porzingis was hurt Wednesday when he and Justise Winslow were pursuing a loose ball on the baseline and Winslow stepped on Porzingis' right foot. Porzingis' foot turned during the first-quarter sequence, and he appeared to roll his ankle.
He stayed on the floor for several minutes before walking to the locker room while being supported by a teammate and a team staffer.
A subsequent X-ray and MRI revealed no structural damage. Porzingis didn't practice in the two days leading up to Sunday's game but said Friday that his swelling had decreased since the initial injury. He will continue to receive treatment while the team is in Indiana.