Henderson missed Wednesday night's game against the Wizards, but returned to play against the 76ers.
However, coach Paul Silas says he believes Henderson might have injured his back during a fall Friday night.
Matt Carroll gets the start in place of Henderson.
Silas said guard D.J. Augustin and forwards D.J. White and Corey Maggette likely won't play in the team's upcoming four-game road trip due to injuries, but there's a chance guard Reggie Williams will return to practice Monday.