LeBron James, Dwyane Wade and Chris Bosh started together for the first time in eight games. Bosh had missed the last four games with a sprained left ankle, while Wade missed Miami's last game with a sprained right wrist.
Wade was a late scratch Friday night but an MRI showed no damage in the wrist. He missed the Heat's victory over the Detroit Pistons after injuring the wrist Thursday in New York.
James has also missed two games recently with an ankle injury.
The injuries have slowed down the Heat, who are 2-6 in their past eight games, a span that followed a stretch of 20 wins in 21 games earlier in the season.
The Heat also had Mike Miller, who was bothered by a leg injury Friday night.
The Thunder were without starting shooting guard Thabo Sefolosha for a second straight game because of a left knee sprain.
Information from ESPN.com's Brian Windhorst and The Associated Press was used in this report.