Wade skipped the Heat's shootaround and is planning to get an X-ray before the game (ESPN, 10:30 ET). If the X-ray is negative, he is planning to warm up to see how the foot responds before making a decision on playing.
Wade suffered the injury in the third quarter Monday night during the Heat's 113-110 win against the Houston Rockets. He stepped on teammate Chris Bosh's foot and turned his ankle and foot. Wade returned in the fourth quarter but was limited. He received treatment during the day Tuesday, an off day for the team.
"Hopefully there's nothing wrong and I'll just see if I'm able to put the pressure on I need to to play," Wade said. "Personally I think it's a deep bruise. I have to make sure it's nothing more than that because it's on the bone."
Wade already missed a game during the Heat's current six-game road trip, Friday's game in Atlanta, due to a cold. He has been dealing with several nagging injuries including a jammed right thumb he suffered Sunday in Memphis.
"I want to play, it's a prime-time game," Wade said, "but I want to feel good."
Wade is averaging 18.4 points for the Heat, who are 6-2 and 2-1 on the road trip. The Clippers are 5-2 and enter the game riding a three-game win streak.