The Dons failed to get off a final shot.
Souley Boum gave the Dons a 65-64 lead on a layup with three seconds left and then fouled McClendon beyond the 3-point line to send him to the line for his first free throw attempts of the night.
McClendon -- who finished with eight points -- put Loyola Marymount (6-10, 1-4 West Coast Conference) ahead 64-58 with 69 seconds to go before Nate Renfro countered with a jumper, Jordan Ratinho made a 3 and Boum's layup.
Boum and Frankie Ferrari led San Francisco (10-8, 2-3) with 12 points each and Ratinho scored 11.
Alessandro Lever and Joshua Braun combined to score 51 points and Grand Canyon kept Chicago State winless in Western Athletic Conference contests with an 86-58 victory on Thursday night.
DJ Laster scored 24 points, making 10 of 14 shots, as Gardner-Webb edged past Presbyterian 61-53 Thursday night to remain perfect on its home floor.
Frank Bartley IV scored 17 of his 26 points in the second half as Louisiana dominated the final period to beat UT Arlington 77-65 on Thursday night to remain alone and unbeaten atop the Sun Belt Conference.