The Dons failed to get off a final shot.
Souley Boum gave the Dons a 65-64 lead on a layup with three seconds left and then fouled McClendon beyond the 3-point line to send him to the line for his first free throw attempts of the night.
McClendon -- who finished with eight points -- put Loyola Marymount (6-10, 1-4 West Coast Conference) ahead 64-58 with 69 seconds to go before Nate Renfro countered with a jumper, Jordan Ratinho made a 3 and Boum's layup.
Boum and Frankie Ferrari led San Francisco (10-8, 2-3) with 12 points each and Ratinho scored 11.
Former Western Michigan player Joeviair Kennedy has been sentenced to at least 17 years in prison.
Houston, Phoenix, San Antonio and Indianapolis were selected as host cities for the NCAA men's basketball Final Four from 2023-26.
Point guard D.J. Carton, ranked No. 28 in the ESPN 100, has committed to Ohio State, choosing the Buckeyes over Big Ten rivals Michigan and Indiana.