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Eli Cain scored 21 points, Billy Garrett added 15 and DePaul defeated Lamar 80-61 on Tuesday night.
Saint Mary's plays all five of its remaining non-conference games at home against unranked foes, starting with Thursday's game against Texas-Arlington, and that gives the No. 12 Gaels (6-0) a chance to enter West Coast Conference play unbeaten.
Marcus Keene sets a career high with 40 points in Central Michigan's 107-97 victory over Green Bay.