Henry started last week against Illinois but experienced more discomfort on his hand than Purdue had expected. Robinson played most of the game as Purdue fell 44-10 to the Illini.
Robinson would be Purdue's third starting quarterback in an injury-plagued season. Henry has started the last four games after Robert Marve suffered a season-ending knee injury Sept. 25.
"The situation's the same, [Henry] still has the same injury with the same amount of discomfort," Hope said Tuesday. "So with that in mind, rather than assume that he might be able to play on Saturday, we're assuming that he's not. If he can, that's gravy, but we'll get Sean Robinson ready to go."
Henry suffered the laceration Oct. 23 at Ohio State. There was some concern of infection, but Henry has shown no signs of one so far.
"If he could go, he would," Hope said. "I don't know if he can right now."
Adam Rittenberg covers Big Ten football for ESPN.com. He can be reached at email@example.com.