NEW YORK -- Brooklyn Nets point guard Deron Williams received a cortisone shot and a platelet rich plasma injection in both ankles to relieve inflammation following an MRI taken Monday, the team announced Tuesday.
Williams will not play in Wednesday night's game against the Golden State Warriors and will be evaluated at the end of the week, the team said. He is in a walking boot.
Williams did not play Monday due to a sprained left ankle, the same injury that has kept him out of 12 games this season.
The Nets said Williams was treated with a cortisone shot in both ankle joints and a PRP injection in the lateral ligaments of both ankles.
Williams has sprained his left ankle on three occasions this season. He originally sprained it Nov. 15 at Phoenix and missed the next two games before returning Nov. 20 at Charlotte, where he sprained it again and missed another nine games as a result. It is unknown when or how Williams sprained it a third time.
Last season, Williams had three sets of cortisone shots and a PRP injection due to inflammation in both ankles. Those injuries caused Williams to struggle through the first 50 games; he averaged just 16.7 points and 7.6 assists on 41.3 percent shooting over that stretch.
But after taking a week off to rest and a three-day juice cleanse at the All-Star break, Williams averaged 22.9 points and 8.0 assists on 48.1 percent shooting in his final 28 games.
Williams rested during the summer and hoped he'd be able to put the injuries behind him. He suffered a sprained right ankle and a bone bruise during an offseason workout in Utah and missed nearly all of training camp and the preseason as a result.
He hasn't had the same explosiveness he featured in the playoffs last season, and he has yet to dunk in a game this season.
It looked like he was starting to get on track the last two games, as he averaged 25 points on 63 percent shooting.
Last Thursday at Oklahoma City, Williams told reporters he was dealing with an injury but wouldn't reveal what it was and said he was going to play through it.
Williams, 29, is in the second year of a five-year, $98 million contract he signed in the summer of 2012. He is due to make $18.5 million this season, $19.7 million next season and $21 million in 2015-16. Williams will make $22.3 million in 2016-17, though he does have an early termination option.
The Nets (13-21) have been decimated by injury this season. They've lost 75 games due to injury split among seven players. Center Brook Lopez was lost for the season Dec. 20 after fracturing the fifth metatarsal of his right foot at Philadelphia. Williams had been flourishing while playing in a small lineup, which featured fellow point guard Shaun Livingston. Alan Anderson started in place of Williams on Monday.
The Nets will take a season-high-tying three-game winning streak into their matchup with the Warriors.
Mike Mazzeo is a regular contributor to ESPNNewYork.com.