EAST RUTHEFORD, N.J. -- The pain in Shawn Andrews' injured back flared up late Wednesday night. It hadn't subsided by the time he showed up at the New York Giants' practice facility on Thursday morning, so the team sent him to the Hospital for Special Surgery in Manhattan for treatment.
After two days of treatment, the 27-year-old offensive tackle was released from the hospital Saturday morning and is listed as doubtful for Sunday's home game against Jacksonville.
Andrews' ailment is the latest in a rash of injuries to the Giants offensive line.
"He experienced so much discomfort that he was having trouble sleeping. That affected him. So they tried to relieve the tension," Tom Coughlin said on Friday afternoon.
It's unclear what treatment Andrews was receiving, but on Friday afternoon he posted on his Twitter account: "That's a verrrry uncomfortable feeling having needles stuck 7 inches deep into your back! Not as bad as being cut open, but still rough."
If Andrews sits, 2009 second-round pick William Beatty will likely get his first start at left tackle. Beatty, who sat out most of the season with a fractured foot, made four starts at right tackle last year.
The Giants will also be without starting center Shaun O'Hara (foot) and left tackle David Diehl (hip/hamstring) against the Jaguars. Rich Seubert will likely start at center for the third straight week and Kevin Boothe should get the start at left guard.
Andrews practiced on a limited basis on Wednesday before feeling the pain in his back.
The former Philadelphia Eagle previously underwent two back surgeries that kept him sidelined for nearly two seasons.
He needed an epidural last week to play in the Giants' game against the Eagles, his third straight start at tackle.
Coughlin said the epidural was not the source of his latest flare-up.
Offensive coordinator Kevin Gilbride said Andrews had "performed tremendously" in place of Diehl.
"Now we're asking William Beatty to go up and do the same thing," Gilbride said. "It's your chance, it's your opportunity. You've been clamoring for it and you wanted an opportunity, we've wanted to give it and now it's here."
Fortunately for Beatty and the rest of the Giants' depleted offensive line, the Jaguars defense has registered just 20 sacks, the 16th highest total in the league.
The Giants rushing attack, however, has been affected by the rash of injuries.
"It's a challenge, there's no question," Gilbride said. "It's not the way you'd like it, but it's the way it is."
In other injury news, starting wide receivers Hakeem Nicks (lower leg) and Steve Smith (pectoral) are out as expected and punt returner/cornerback Will Blackmon (chest) is questionable, though he believes he will play against Jacksonville.
The team may have added Coe as an insurance plan if Ross is unable to play on Sunday.
Coe, the Colts' fifth-round pick in the 2005 draft, has nine tackles in 11 career games. Blackmon also hinted on Friday that he could see time at cornerback.
Ian Begley is a regular contributor to ESPNNewYork.com.