Manning said he has exchanged text messages with Nicks, who unexpectedly did not attend recent voluntary OTA practices.
"Hopefully he is here tomorrow," Manning said during an appearance for the Guiding Eyes for the Blind Golf Classic at Mount Kisco Country Club. "I expect him to be there tomorrow, so we'll see."
While Manning expects Nicks to be at this week's minicamp, the star quarterback isn't sure about his other wide receiver -- Victor Cruz, who has not signed his one-year restricted free agent tender yet.
Giants coach Tom Coughlin and Manning both sounded as if they were not expecting Cruz to be at the minicamp.
"Victor has to get his business handled so he can get back to work," Manning said.
Neither Nicks nor Cruz showed up for Monday's team physicals, a league source told ESPN NFL Insider Adam Schefter.
Manning and Coughlin have said repeatedly that they would like to have both of their top receivers working in the offseason training program. While Cruz's absence has been anticipated due to his contract, Nicks' no-show was surprising because he had not given Coughlin any indication that he wasn't coming to the voluntary workouts in previous weeks.
The Giants want to extend the contracts of both receivers. Nicks is entering the final season of his deal.
The last time Manning worked with both of his receivers was at Duke University in April, when he and Peyton Manning organized informal workouts with some of their wide receivers.
Manning said last week that he was hoping those workouts "would be a little starter course to the spring. Not a substitute for what we're doing on the field right now."
"This is stuff where we're getting to go against cornerbacks," Manning added. "You get to work your technique."
Nicks could be limited this week at minicamp as he continues to make sure he will be at full strength for the upcoming season. He labored through knee and foot injuries last season and underwent a minor scope procedure on his knee.
"I don't know what he'll do," Manning said. "We'll have to see. We have three practices left, so for me just keep going out there and the guys who are there participating, continue to get them to learn the offense and see if we can make some strides in getting better."
Manning is confident that Nicks and Cruz will be ready when the season begins.
"Hakeem and Victor, they know the offense," Manning said. "They know how to get better. With Hakeem, we got to make sure he is completely healthy and something he has been battling for a while and make sure at the start of the season he is 100 percent.
"(Training camp) is when we will have time to work on a lot of things."