The designation means Brown has to miss at least six weeks of practice and at least eight weeks of games. Because the Giants have a bye in Week 9, that means the earliest Brown will be eligible to play is Week 10 against the Oakland Raiders.
Brown, who fractured his left leg Thursday in the Giants' preseason game at New England, sort of broke the news himself Tuesday on Twitter:
See y'all week 8
— Andre Brown (@drebrown35) September 3, 2013
The Giants filled Brown's spot on the 53-man roster Wednesday by signing defensive end Adewale Ojomo from their practice squad for Sunday's opener at Dallas. Offensive lineman Sam Baker was signed to the practice squad.
Ojomo was on the Giants' roster last season but played in only one game. He was waived Saturday in the final cut.
Information from The Associated Press was used in this report.