The Tennessee Titans went within their division to fill a big hole on their offensive line.
"Well, hopefully, if I'm doing my job he won't have to get outside the pocket too much," Scott said. "But I don't think it's really going to change a lot of what I do."
The Tennessean reported that Scott, 26, will be paid an average of $5 million per season.
The unrestricted free agent started 57 games for the Colts, including a current streak of 55 straight. All but four of his starts came at right guard.
Scott has eight career playoff starts, including the Colts' Super Bowl win in 2006. He was the fifth-round pick of the Colts in the 2004 NFL draft.
The Titans also hired Earnest Byner as their running backs coach.
Byner, a former Pro Bowl running back, said he looks forward to working with LenDale White.
"I like some of the vision he has, some yards after contact, protects the ball good when he gets into the pile," Byner said.
Information from The Associated Press was used in this report.