Winslow was hurt when he was tackled in front of Buffalo's bench while making a 16-yard reception that set up Cleveland's game-winning field goal. The five-year veteran, who has had numerous injuries during his career, was driven to the ground by Bills linebacker Paul Posluszny and came up wincing in pain.
Winslow briefly left the field but returned and was the intended receiver on an incompletion by quarterback Brady Quinn before Phil Dawson kicked a 56-yard field goal in Cleveland's 29-27 win. Winslow finished with three catches for 40 yards.
"We'll check him out and see if he'll be able to do much this week," Browns coach Romeo Crennel said.
Crennel said defensive tackle Shaun Smith will also have an MRI on a calf injury. In addition, the Browns had several other players banged up. Running back Jerome Harrison, who had a 72-yard touchdown run, injured his hamstring. Safety Sean Jones (ankle), nose tackle Shaun Rogers (shoulder) and running back Jason Wright (neck) were also hurt.