Chambers must clear waivers in order to play for another team. Each team will have chance to claim him by 4 p.m. Tuesday.
If another team claims Chambers, the Chargers won't have to pay the $2.25 million they owe him.
Chambers had one catch for 20 yards Sunday against Oakland. He has only nine catches for 122 yards and one touchdown this season.
Chambers was obtained at the trading deadline in 2007 from Miami for a second-round draft pick, and helped the Chargers reach the AFC Championship Game that season.
Adam Schefter is an ESPN NFL Insider. Information from The Associated Press is included in this report.