Coach Tom Cable says Bush caught the ball and ran with the ball during practice Friday. Cable says it will be a game-time decision whether last year's leading rusher suits up for the opener.
Darren McFadden will get the bulk of the work against the Titans if Bush cannot go.
Defensive tackle Desmond Bryant is also questionable with an elbow injury. Receiver Chaz Schilens (knee), linebacker Travis Goethel (lower back) and cornerback Walter McFadden (hamstring) have been ruled out.