Williams missed Friday's practice and his status is very much in doubt until pregame warm-ups.
Wide receiver Andre Johnson remains questionable with his ankle injury. However, Johnson was encouraged because he was on the practice field Friday on a limited basis. Johnson missed last week's game against the Oakland Raiders.
In addition, wide receiver Jacoby Jones is doubtful with a calf injury. He hasn't practiced all week and is expected to miss the game.
Running back Derrick Ward is questionable with a rib injury.
Linebacker Kevin Bentley is out with a knee injury.
John Clayton is a senior NFL writer for ESPN.com.