Colts wide receiver Pierre Garcon will be back in the lineup Sunday when Indianapolis hosts undefeated Kansas City.
Garcon was a full participant in practice Thursday after missing the last two games with a hamstring injury. He has just four receptions for 54 yards and zero touchdowns this year after hauling in 765 yards and four touchdowns last season.
Fellow wideout Austin Collie returned to practice on Friday, giving him a chance to play against the Chiefs after missing workouts on Wednesday and Thursday.
Collie has not missed any games this year and leads the Colts with five touchdowns. Collie is also second on the team with 32 receptions and 398 receiving yards.
Running backs Donald Brown and Mike Hart have yet to practice this week and are expected to sit out Sunday, along with safety Bob Sanders (biceps), wide receiver Anthony Gonzalez (ankle) and linebacker Kavell Conner (foot).
The Colts are hopeful left tackle Charlie Johnson will start despite a foot injury.
ESPN.com senior NFL writer John Clayton contributed to this report.