The Saints lost 23-13 to the Buccaneers and are locked into the fifth playoff seed in the NFC after Atlanta's 31-10 win over Carolina.
Graham hurt his left leg making a touchdown catch in the first quarter. He limped to the sideline and went to the locker room. The Saints already were playing without tight ends Jeremy Shockey (groin) and David Thomas (right knee).
Jenkins appeared to hurt his right knee while tackling LeGarrette Blount in the first quarter. Jenkins limped to the sideline where trainers wrapped his knee.
Ivory came off the field after a short run in the second quarter and went to the locker room with an apparent leg injury.
Information from The Associated Press contributed to this report.