The Vikings made the announcement Thursday. The all-star game is Sunday in Hawaii.
Henderson started all 16 games in 2010 and tied for the NFL lead among linebackers with three interceptions.
Henderson broke his leg during a December 2009 game and had a titanium rod put in. The injury required months of rehabilitation and put his career in jeopardy. But Henderson vowed to return
He did so well that the Vikings medical staffers have presented Henderson's case to colleagues as a model for treatment.