Drew Brees: Against the NFL's No. 1 defense, Brees had his most productive game of the season. Brees completed 23 of 30 passes for a season-high 369 yards and four touchdowns to lead New Orleans to a 48-27 victory over the previously unbeaten Giants. Brees completed 15 straight throws during one stretch -- two short of the franchise record he already owns.
Tom Brady: Wintery conditions in Foxborough didn't slow Brady. In fact, the Patriots' signal-caller had one of the best games of his career. Brady threw six touchdown passes, including a record five in the second quarter, as the Patriots routed Tennessee 59-0. Brady, who gave way to Brian Hoyer in the third quarter, finished 29-of-34 for 380 yards.
Matt Schaub: Schaub tied his career high with four touchdown passes -- two of them to tight end Owen Daniels -- to lead the Texans to a 28-17 victory at Cincinnati. Schaub was 28-of-40 for 392 yards; it was his fourth 300-yard passing game of the season.
Thomas Jones: On a day when the Jets' passing game struggled (see below), Jones was able to provide a spark. Jones rushed for a Jets-record 210 yards and one TD on 22 carries in New York's 16-13 overtime loss to Buffalo.
Maurice Jones-Drew: Jones-Drew rebounded from a pair of subpar performances (23 rushing yards in Week 5; 14 yards in Week 4), running for 133 yards and three touchdowns as the Jaguars edged the Rams 23-20 in overtime. It was Jones-Drew's second three-TD game of the season.
Sidney Rice: Rice had six catches for a career-high 176 yards in the Vikings' 33-31 victory over Baltimore. With Minnesota trailing 31-30 late in regulation, Rice caught a 58-yard pass from Brett Favre, setting up Ryan Longwell's go-ahead field goal. Rice's previous season high in receiving yards was 70 (Week 4).
The Panthers' run game: After being held in check for much of the season, the Panthers' power running tandem of DeAngelo Williams and Jonathan Stewart re-emerged in Week 6. Williams rushed for 152 yards on 30 carries and scored two TDs, including the game winner (a 1-yarder with 29 seconds left), in a 28-21 victory over the Buccaneers. Stewart added 110 yards and one TD on 17 carries.
Kerry Collins: As Brady flourished in the snow, Collins languished at the other end of the spectrum. Collins completed only 2 of 12 passes for minus-7 yards and one interception against the Patriots. He was replaced by Vince Young in the third quarter.
Mark Sanchez: After a sizzling start to his NFL career, Sanchez can't seem to shake the growing pains. For the second time in three weeks, the Jets' rookie quarterback was unproductive and mistake-prone. Sanchez completed 10 of 29 passes for 119 yards and five interceptions in the loss to Buffalo.
The Bengals' defense: The Bengals, who lost leading pass-rusher Antwan Odom (Achilles) and starting DE Domata Peko (knee) to injuries, were picked apart by Schaub and the Texans' passing game (see above). Cincinnati surrendered 472 total yards in the 28-17 loss, 77 yards more than their previous season high.
The Lions' QBs: Without injured star WR Calvin Johnson, the Lions' passing game was virtually nonexistent in a 26-0 loss at Green Bay. Daunte Culpepper, subbing for injured starter Matthew Stafford, was 6-of-14 for 48 yards and one interception before leaving with a hamstring injury. Replacement Drew Stanton completed only 5 of 11 passes for 57 yards and two picks.